Charles D. Papageorgiou, Associate Director, Takeda Pharmaceuticals
Continuous processing and flow chemistry are becoming increasingly common technologies used in the manufacture of active pharmaceutical ingredients. This symposium will focus on both chemistry and engineering solutions that have enabled process intensification, seamless scale-up as well as the development of environmentally friendly processes. Case studies will be presented from leading academics and industrialists highlighting the use of such technologies as well as the development of suitable manufacturing strategies.
Session Organizer: David Leahy, Associate Director, Process Chemistry, Takeda Pharmaceuticals
The development of new synthetic methodologies and strategies has been the cornerstone upon which sustainable industrial processes are built. The pure research advances arising from academia fuel the world’s industrial innovation, while also training the scientific leaders of tomorrow. This special session highlights the research of graduate students and post-doctoral fellows across the broader organic chemistry community which has the potential to impact sustainable industrial chemistry. The ACS GCI Pharmaceutical Roundtable will provide 8 travel grants of up to $1000 to attend the conference and provide a 20 minute oral presentation during this session. A poster session will accommodate additional presenters. All presenters will be invited to attend the Student Conference Kick-off, and the ACS GCI 8th Annual Industrial Roundtable Poster reception during the conference.
Session Organizers: John Frazier, Senior Technical Director, Hohenstein Institute of America; Scott Echols, Scott Echols Group, LLC; Robert Buck, Technical Fellow on Sustainability, The Chemours Company
Material and chemical manufacturers are redefining what they make, how they make it and how their inputs impact the processes and footprint for creating consumer and industrial products. Greener, more sustainable materials, chemistry and engineering are widely embraced as the way to create and deliver high performance products, minimize environmental impacts and advance circular life cycles. In this session, material, chemical and process innovations transforming consumer and industrial products will be presented. Papers describing research efforts and commercial successes in products such as apparel and footwear as well as in the automotive, home furnishings, and electronics accessories sectors are requested.
Session Organizers: Jane E. Wissinger, Professor, University of Minnesota; Michael T. Wentzel, Assistant Professor, Augsburg University
This symposium seeks to demonstrate how educators are engaging students in the classroom and laboratories by sharing new innovations in sustainable materials. Society’s dependence on plastics and other resilient fossil-fuel based materials, as well as their potentially negative impact on human health and the environment, is a topic that resonates with students of all levels. We are seeking abstracts which illustrate the use of green methodologies to prepare products which are: derived from renewable feedstocks; designed for degradation; reprocessed and/or recycled; or inherently safer. Of special interest are curriculum materials which meet the 2015 Committee on Professional Training Guidelines requirements to include synthetic polymers, biological macromolecules, supramolecular aggregates, meso-or nanoscale materials and simultaneously include green chemistry and engineering principles. The session is open to K-12, undergraduate, and graduate instruction as well are outreach initiatives. A goal of the symposium will be for each presenter to provide a live or videotaped demonstration of their projects to share with the audience.
Session Organizer: Kevin Maloney, Director, Process Chemistry, Merck
In the past two decades, Green Chemistry has challenged chemists to consider environmental impacts in developing synthetic methodologies and designing manufacturing processes. Despite these efforts, the pharmaceutical industry is among the largest waste producing sectors in all chemical industries, partly due to its typical requirements of multi-step synthesis and stringent regulatory quality standards. While efficient, concise, and convergent synthetic routes to complex molecules are essential for their sustainable production; of equal importance is the efficiency of individual processes that comprise each step along the synthetic route. Therefore, innovative chemistry and process development are instrumental in the design and development of green and sustainable small molecule manufacturing processes. This session will explore how innovative synthetic methodologies, prediction tools, high throughput experimentation, catalysis, solvent selection, recycling, and minimization of unit operations play a vital role in developing a green and sustainable process.
Session Organizers: Jennifer Y. Tanir, Founder, Toward Safer LLC; M. Barclay Satterfield, Eastman Innovation Center Leader, Eastman Chemical Company
One of the barriers to the implementation of sustainable chemistry is strong integration and acceptance throughout the supply chain. Despite many individual single-product or single-company successes, or a few advances in limited sectors’ supply chains, there is still a need for widespread agreement on sustainability goals and cooperation throughout supply chains. This 1-day workshop will focus on formulated household products and attempt to distill the learnings from individual successes into a plan for widespread adoption. The workshop will build on related conversations at the 2017 GC&E Conference and a Green Chemistry article by the ACS GCI Formulators’ Roundtable. The discussions will bring together the technical experts in formulated household products along with learnings from other sectors that can be applied, new ways of thinking, and students who can develop future solutions. The format will be interactive including invited talks as well as brainstorming and problem-solving sessions with the goal of developing a plan (and publication) to better incorporate sustainable chemistry in the supply chain. The workshop will explore: (1) How to drive change, with lessons from past successes; (2) Goals, barriers to achieving those goals, and consensus on what success looks like; (3) Developing a plan forward, including recommendations. The workshop is being organized in partnership with the ACS Committee on Environmental Improvement (CEI).
Session Organizers: Amy Cannon, Ph.D., Beyond Benign; Dalila Kovacs, Ph.D., Grand Valley State University; Pamela Spencer, Ph.D., Angus Chemical; Saskia van Bergen, Washington State Department of Ecology
Toxicology tools and concepts are essential in chemistry courses and programs to develop an understanding of toxicological principles and chemical safety that are traditionally absent from the chemistry curriculum. These concepts are also important in the design of chemical products and processes that have reduced health and environmental hazards. Toxicology can enable scientists to better predict hazards at the molecular level, therefore avoiding the use and generation of hazardous chemicals. Today, there is a movement towards teaching toxicology concepts to chemistry students and professionals in order to better prepare scientists with the skills to design products and processes with reduced hazards.
This symposium will feature: 1) professional toxicologists and chemists who actively use toxicology tools in their practical design of safer chemical products and processes, and 2) faculty members who have adopted toxicology concepts and practices within their chemistry courses and programs. Symposium speakers will provide short lectures on their area of expertise and demonstrate with tools they use in their daily practice, and share curriculum models.
Session Organizer: Wilfried Braje, Principal Scientist, AbbVie
This symposium features the development of new synthetic chemistry from both academic and industrial labs that document not only that waste creation can be minimized, but that by going green, “faster, better, cheaper” processes oftentimes can be anticipated.
Notwithstanding the extraordinary advances being made in synthetic organic chemistry and organometallic catalysis, in particular, the manner in which this discipline has been, and continues to be practiced is simply not sustainable. The enormous amounts of organic waste being generated, the investment of energy in the form of heating and cooling of reactions, and the consumption of endangered metal-catalysts at an ever-increasing rate have all become important considerations for a sustainable future. Fortunately, new technologies are starting to accrue suggesting that synthetic chemistry need no longer be done at the expense of the environment; that the same, useful processes can, in fact, be developed hand-in-hand with the principles of green chemistry.
Session Organizers: Paul Thornton, Technology Development Manager, GreenCentre Canada; Laura Reyes, Career Development Leader, Chemical Institute of Canada
Entrepreneurship in chemistry offers the opportunity to bring new sustainable products and processes to the marketplace. Start-up companies and small and medium enterprises (SMEs) have some advantages over larger corporations when it comes to creating and marketing a product or technology (e.g. greater agility in a rapidly changing market, narrower focus on a single product or market, etc.). However, entrepreneurship also presents many diverse challenges and risks to stakeholders.
This symposium, through a mix of invited and contributed talks as well as an interactive component, aims to discuss the various stages of commercialization for green chemistry technologies. Entrepreneurial leaders and stakeholders of chemistry-based start-ups and SMEs will provide their perspectives on the challenges, opportunities, and rewards that arise in advancing sustainable chemistry products and processes. Speakers will come from diverse backgrounds contributing to entrepreneurship and commercialization, such as company founders, intellectual property lawyers and patent specialists, and venture capitalists and funding experts.
Abstract submissions are encouraged from anyone involved in the commercialization of chemistry, academics and business professionals alike. Topics covered by talks may include but are not limited to:
- Technical challenges and solutions (performance validation, product testing, process scale-up, manufacturing)
- Funding (securing investment, leveraging grants)
- Team and leadership (business leadership and advisors, non-technical skills required, collaborations and partnerships)
- Intellectual property (protecting technologies with patents or trade secrets)
- Value proposition, marketing, and pivoting (market validation, disruptive vs incremental technologies, risk mitigation, changes in company vision, marketing of “green” products)
- Path to market and exit strategies (preparing a commercial launch, company vision and potential growth)
The interactive component of this symposium will build on the invited and submitted talks, leveraging expertise of speakers and conference participants, leading to an exchange of ideas and approaches that will highlight what resources and solutions are available to the entrepreneur with a sustainable technology who aims to succeed in the rapidly changing chemical enterprise.
Session Organizers: Anthony Noce, Vice President, EHS Management Systems, Tetra Tech; Lauren Heine, Ph.D., Executive Director, Northwest Green Chemistry
Many chemists are inspired to use their skills to address real world challenges to human health and sustainability. To work on basic and/or applied research challenges that are linked to such challenges is very different from bringing products to the marketplace that actually become sufficiently successful to provide the desired benefits. The benefits may be novel or they may be designed to replace other products because of their impacts on natural resources, due to the generation or use of toxic substances, or because they generate poorly managed waste in a linear “take, make, waste” system of industrial production.
In this session, we will explore both the drivers and barriers for new green chemistry and engineering technology development in products, as well as strategies to enhance the drivers while overcoming the barriers. Drivers are diverse and may or may not be in alignment. Examples include environmentally preferable procurement, regulation, research support, scale up support, voluntary supply chain initiatives, technical standards and/or ecolabels, awards and prizes, preferential government purchasing, and so much more. In contrast, there are many obstacles, including lack of funding, lack of access to entrepreneurial or business expertise, limited market awareness, entrenched products with dominant market share, procurement experts with limited understanding of alternative technologies, standards that prefer older technologies driving incremental improvements rather than real innovation, regulatory requirements, lack of access to scale up resources, cultural inertia, and more.