Biocatalysis Success Stories

Organizers: Kevin Maloney, Director, Merck Process Chemistry, Rahway, NJ, USA; Jennifer Obligacion, Senior Scientist, Merck Process Chemistry, Rahway, NJ, USA

The facile access to engineered enzymes has led to the widespread adoption of biocatalysis in complex molecule synthesis in both academic as well as industrial laboratories. This session will attempt to highlight the mostly untapped potential of bio-catalysis and protein engineering in developing new synthetic methodologies that unlock new chemical spaces and are green and sustainable. In addition, the chemistry and engineering challenges associated with developing green and sustainable biocatalytic transformations in this context will be discussed, along with several success stories with its implementation.