Unlocking the Power of Enzymes: Biocatalysis as an Enabling Tool in Complex Molecule Synthesis

Organizers: Cindy Hong, Sr. Scientist, Merck; Kevin Maloney

The facile access to engineered enzymes has led to the widespread adoption of biocatalysis in complex molecule synthesis in both academic as well as industrial laboratories. This session will attempt to highlight the mostly untapped potential of bio-catalysis and protein engineering in developing new synthetic methodologies that unlock new chemical space and are green and sustainable. In addition, the session will highlight the chemistry and engineering challenges associated with developing biocatalytic transformations, and how computational chemistry along with a detailed mechanistic understanding can aid in developing robust processes.